cancer

Tumors overexpress certain genes to survive a growing pile of harmful mutations, a trait that scientists could exploit to target with drugs.

Algorithms can now glean ever more molecular and genetic information from images of stained tissue, but some researchers worry that we can’t follow their logic.

Khalid Shah engineers stem cells to deliver cancer therapeutics directly to tumors, thereby increasing their efficacy.

Oncolytic viruses can help glioblastoma respond to immunotherapy.

Fyza Shaikh investigates how microbes shape cancer patients’ health and recovery.

A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.

Scientists hack the locust brain to identify the unique odor signatures of oral cancers.

New research may make immunotherapy possible for hard-to-treat brain tumors.

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.

Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.

Although scientists often assume that synonymous mutations don’t cause any biological effects because they don’t alter the amino acid code, recent research shows that they can influence transcription and translation in a variety of ways. 

Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.