immunology

Jie Sun shares how his curiosity, creativity, and motivation to address clinical public health needs steer his research in immunology and infectious disease.

Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.

Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.

Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education.

Ana Teresa Freitas discussed how individual variation in vitamin D synthesis and metabolism influences susceptibility to upper respiratory viruses.

Male patients who recover from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges than female patients.

mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants. 

Researchers shed light on the immunometabolism of respiratory infection, providing an avenue towards safer COVID-19 therapeutics for those affected by metabolic disorders.

New research may make immunotherapy possible for hard-to-treat brain tumors.

By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.

Scientists identified a species of Subdoligranulum that may drive disease.

Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 

Engineering of a novel device to treat T1D, featuring local immunosuppression and a vascularized cell reservoir to prolong islet cell survival.

The changes may help explain the link between maternal infection and autism, though more research is needed.