physiology

A new, invisible fluorescent patch continuously monitors blood glucose levels in mice.

Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.

By delivering mRNA to the skin of mice in utero, researchers showed a proof-of-concept for shuttling gene therapies to skin cells before birth.

Exercise drives the liver to produce the CES2 enzyme, which circulates in blood and delivers some of the benefits of exercise in mice. 

Rare samples saved 35 years ago helped researchers map gene expression and cell differentiation in first trimester placentas.

A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

The sympathetic nervous system influences gene expression in the heart to regulate the day-night cycle of resting heart rate.

By mechanically inducing the expansion of cranial sutures in young adult mice, researchers stimulated stem cell proliferation that is key to healing bone injuries.

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.

Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.

Scientists reveal how the intimate link between hair follicles and wound healing is more than skin deep.

An implantable device stimulates muscle contraction and prevents muscular atrophy in mice.

The experimental device, known as MAGENTA, forces muscles to contract, simulating natural movement. 

The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.