genetics

Tumors overexpress certain genes to survive a growing pile of harmful mutations, a trait that scientists could exploit to target with drugs.

Lasker Award winner Evelyn Witkin discovered the mechanism for DNA repair following UV damage.

By studying the genomes of more than 24,000 individuals, researchers discovered rare genetic mutations that may shed light on mechanisms underlying schizophrenia.

By delivering mRNA to the skin of mice in utero, researchers showed a proof-of-concept for shuttling gene therapies to skin cells before birth.

By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.

Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.

Research on human embryos is usually limited to the first 14 days of development, but as scientific capabilities improve, some argue that it is time to go further.

A single approach rarely addresses all research needs. Learn when and how to employ sequencing and PCR-based methods.

Fungi disrupt microbial communities on cheese by making antibiotics. 

Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.

Ana Teresa Freitas discussed how individual variation in vitamin D synthesis and metabolism influences susceptibility to upper respiratory viruses.

Endonuclease R changed Richard Roberts’ career trajectory and created an industry.

As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.

Coaxing bacteria into taking up recombinant DNA was arduous until Douglas Hanahan took action.