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Dendritic Cell activate T cells, trigger immune responses, they are responsible of cells protection of the body.
Circadian Signaling Affects T Cell Responses to Vaccination
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
Circadian Signaling Affects T Cell Responses to Vaccination
Circadian Signaling Affects T Cell Responses to Vaccination

Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.

Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.

circadian rhythms

EKG readout
The Circadian Rhythm of the Heart Rate
Katherine Paulin, PhD | May 31, 2023 | 3 min read
The sympathetic nervous system influences gene expression in the heart to regulate the day-night cycle of resting heart rate.
The face of a young woman and the face of an old man surrounded by mechanical clocks.
Daily Gene Expression Rhythms Vary with Sex and Age: Study
Alejandra Manjarrez, PhD | Feb 2, 2023 | 3 min read
By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.
Learn about the latest research on optimal vaccine-induced immune responses
Modulating the Immune Response to Vaccines
The Scientist’s Creative Services Team | 1 min read
Researchers uncover innovative natural approaches to fine-tune immunity from vaccination.
A man working at a computer late at night
Shift Work Early in Life Results in Increased Stroke Severity in Middle Age
Jennifer Zieba, PhD | Jan 11, 2023 | 3 min read
Researchers found that shifted sleep/wake cycles in young rats result in increased functional deficits and mortality following stroke later in life.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Newborn baby rats lie in a basket
Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains
Bianca Nogrady | Sep 12, 2022 | 2 min read
Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.
Fluorescent microscopy of a healthy intestinal organoid and a tumor spheroid
Internal Clock Disruptions Increase Colon Cancer Risk in Mice
Shafaq Zia | Aug 19, 2022 | 3 min read
Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.
Artist’s rendition of metastatic cancer cells with yellow nuclei and green cell bodies extending into blue tendrils.
While the Body Rests, Breast Cancer Spreads More Aggressively
Alejandra Manjarrez, PhD | Jun 23, 2022 | 4 min read
More cancer cells are shed from primary tumors when individuals are asleep than when they’re awake, according to observations in mouse models and a small cohort of breast cancer patients.
Segmented filamentous bacteria artificially colored in green attach to the intestinal wall of a mouse
Gut Microbes Help Coordinate Immune Activity in Mice
Catherine Offord | Jul 29, 2021 | 4 min read
The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.
illustration of multiple clocks arranged in the shape of a brain
How Early-Morning Light Exposure Makes Mice Less Depressed
Bianca Nogrady | Jul 22, 2021 | 4 min read
A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light.
A bar of milk chocolate with the foil peeled back and a bite taken out
Q&A: Eating Milk Chocolate in the Morning Boosts Fat Metabolism
Amanda Heidt | Jun 30, 2021 | 6 min read
A study of 19 postmenopausal women found that eating a bar of chocolate in the morning affected their bodies differently than eating it at night, but neither led to weight gain.
Malaria Parasites’ Biological Clocks Coordinate Cell Destruction
Abby Olena, PhD | May 14, 2020 | 3 min read
Two studies show that Plasmodium—the genus of protozoans that cause malaria—have an internal sense of time that synchronizes with their host’s circadian rhythms and allows the parasites to collectively attack blood cells.
Light Enables Long-Term Memory Maintenance in Fruit Flies
Diana Kwon | May 1, 2020 | 2 min read
Under constant darkness, Drosophila’s ability to form lasting memories is impaired.
Circadian Clock Genes Help a Crop Pest Adapt to Climate Change
Emily Makowski | Jan 13, 2020 | 3 min read
As global temperatures rise and winters shorten, caterpillars of the corn borer moth are emerging earlier in parts of the US thanks to changes in two genes, researchers find.
Sleep Study in Antarctica Explores Role of Cultural Differences
Alejandra Manjarrez, PhD | Dec 1, 2019 | 4 min read
Habits such as napping might influence how humans cope with extreme environments, such as those at a polar research facility in winter.
a plate with fruits and vegetables arranged into the shape of a clock
People at Rest Burn More Calories in the Afternoon
Shawna Williams | Nov 8, 2018 | 2 min read
Circadian rhythms heavily influence how our bodies use energy, a small study suggests.
Infographic: The Role of Circadian Clocks in Muscle
Diana Kwon | Sep 1, 2018 | 2 min read
Timekeepers in muscle help mediate metabolism, and may influence neurological processes such as sleep.
Muscle Clocks Play a Role in Regulating Metabolism
Diana Kwon | Sep 1, 2018 | 9 min read
Just 20 years ago, scientists didn’t even realize muscles had their own circadian clocks. Now they are beginning to appreciate their importance in health. 
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Abby Olena, PhD | Aug 30, 2018 | 3 min read
Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.
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