immunology

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.

Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.

Self-contained synthetic E. coli resistant to viral infection could prove invaluable to the biotechnology industry by increasing product consistency and reducing safety concerns. 

SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 

Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.

The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.

Researchers find that bacteria stimulate a headache-causing pain pathway to suppress the immune system and infect the brain. 

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.

Males recovered from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges.

Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.